Self-Assembly and Multifaceted Bioactivity of a Silver(I) Quinolinate Coordination Polymer.

ABSTRACT: Coordination polymers have emerged as a new class of potent biologically active agents due to a variety of important characteristics such as the presence of bioactive metal centers and linkers, low toxicity, stability, tailorable structures, and bioavailability. The research on intermediate metabolites has also been explored with implications toward the development of selective anticancer, antimicrobial, and antiviral therapeutic strategies. In particular, quinolinic acid (H₂quin) is a recognized metabolite in kynurenine pathway and potent neurotoxic molecule, which has been selected in this study as a bioactive building block for assembling a new silver(I) coordination polymer, [Ag(Hquin)(μ-PTA)]_n·H₂O (1). This product has been prepared from

SUBMITTER: Jaros SW 

PROVIDER: S-EPMC8527454 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature