Understanding population structure in an evolutionary context: population-specific FST and pairwise FST.

ABSTRACT: Populations are shaped by their history. It is crucial to interpret population structure in an evolutionary context. Pairwise FST measures population structure, whereas population-specific FST measures deviation from the ancestral population. To understand the current population structure and a population's history of range expansion, we propose a representation method that overlays population-specific FST estimates on a sampling location map, and on an unrooted neighbor-joining tree and a multi-dimensional scaling plot inferred from a pairwise FST distance matrix. We examined the usefulness of our procedure using simulations that mimicked population colonization from an ancestral population and by analyzing published human, Atlantic cod, and wild poplar data. Our results demonstrated that

SUBMITTER: Kitada S 

PROVIDER: S-EPMC8527463 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature