Crafting for a better MAGIC: systematic design and test for Multiparental Advanced Generation Inter-Cross population.

ABSTRACT: Multiparental Advanced Generation Inter-Cross (MAGIC) populations are valuable crop resources with a wide array of research uses including genetic mapping of complex traits, management of genetic resources and breeding of new varieties. Multiple founders are crossed to create a rich mosaic of highly recombined founder genomes in the MAGIC recombinant inbred lines (RILs). Many variations of MAGIC population designs exist; however, a large proportion of the currently available populations have been created empirically and based on similar designs. In our evaluations of five MAGIC populations, we found that the choice of designs has a large impact on the recombination landscape in the RILs. The most popular design used in many MAGIC populations has been shown to have a bias in recombinant hap

SUBMITTER: Yang CJ 

PROVIDER: S-EPMC8527519 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature