Visual acuity is correlated with ischemia and neurodegeneration in patients with early stages of diabetic retinopathy.

ABSTRACT:

Purpose

We investigated the effects of retinal ischemia, neurodegeneration, and subclinical edema on best-corrected visual acuity (BCVA) in the early stages of diabetic retinopathy (DR).

Methods

Ischemia was evaluated by the microvascular parameters measured by optical coherence tomography angiography. Neurodegeneration and subclinical edema were identified by the intraretinal layer thickness obtained by optical coherence tomography. Eyes with nonproliferative diabetic retinopathy (n = 132) from 89 patients were analyzed. Eyes were classified as having normal BCVA (n = 88 [66.7%], Snellen equivalent ≥ 20/20) or decreased BCVA (n = 44 [33.3%], Snellen equivalent < 20/20). The prevalence of ischemia, neurodegeneration, and subclinical edema was explored in patients with and wi

SUBMITTER: Li J 

PROVIDER: S-EPMC8527732 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature