A comprehensive review of respiratory, autonomic and cardiovascular responses to intermittent hypoxia in humans.

ABSTRACT: This review explores forms of respiratory and autonomic plasticity, and associated outcome measures, that are initiated by exposure to intermittent hypoxia. The review focuses primarily on studies that have been completed in humans and primarily explores the impact of mild intermittent hypoxia on outcome measures. Studies that have explored two forms of respiratory plasticity, progressive augmentation of the hypoxic ventilatory response and long-term facilitation of ventilation and upper airway muscle activity, are initially reviewed. The role these forms of plasticity might have in sleep disordered breathing are also explored. Thereafter, the role of intermittent hypoxia in the initiation of autonomic plasticity is reviewed and the role this form of plasticity has in cardiovascular and he

SUBMITTER: Puri S 

PROVIDER: S-EPMC8527806 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature