Shear Induced Non-Linear Elasticity Imaging: Elastography for Compound Deformations.

ABSTRACT: The goal of non-linear ultrasound elastography is to characterize tissue mechanical properties under finite deformations. Existing methods produce high contrast non-linear elastograms under conditions of pure uni-axial compression, but exhibit bias errors of 10-50% when the applied deformation deviates from the uni-axial condition. Since freehand transducer motion generally does not produce pure uniaxial compression, a motion-agnostic non-linearity estimator is desirable for clinical translation. Here we derive an expression for measurement of the Non-Linear Shear Modulus (NLSM) of tissue subject to combined shear and axial deformations. This method gives consistent nonlinear elasticity estimates irrespective of the type of applied deformation, with a reduced bias in NLSM values to 6-13%.

SUBMITTER: Goswami S 

PROVIDER: S-EPMC8527856 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature