Geriatric assessments and frailty scores in multiple myeloma patients: a needed tool for individualized treatment?

ABSTRACT:

Purpose of review

Multiple myeloma is a disease of elderly adults. Improvement in survival has occurred because of biological insights and novel agents. Therapeutic options involve choices today, thus have become more complex. Demographics have led to an increased number of elderly patients and age may be associated with a poorer outcome but is not the only prognostic predictor today.

Recent findings

To evaluate patients' health status rather than their chronological age alone, frailty scores and functional geriatric assessments are used to identify prognostic groups, avoid adverse events, compare clinical trials and tailor treatment. As most clinical trials exclude frail elderly patients, those enrolled therein are often younger and healthier than the typical multiple myelo

SUBMITTER: Moller MD 

PROVIDER: S-EPMC8528138 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature