Hypertension management in elderly with severe intracerebral hemorrhage.

ABSTRACT:

Objective

To explore the effect of individualized blood pressure (BP)-lowering treatment on the outcomes of elderly patients with severe intracerebral hemorrhage (ICH).

Methods

We performed an exploratory analysis of Controlling Hypertension After Severe Cerebrovascular Event (CHASE) trial, which was a multicenter, randomized, controlled clinical trial. Patients with severe ischemic or hemorrhagic stroke (defined as GCS ≤ 12 or NIHSS ≥ 11) were randomized into individualized versus standard BP-lowering treatment in CHASE trial. In this exploratory analysis, patients with severe ICH were included. The primary outcome was the percentage of patients with 90-day functional independence defined as modified Rankin Scale (mRS) ≤2.

Results

We included 242 patients with severe

SUBMITTER: Zhao J 

PROVIDER: S-EPMC8528461 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature