Relationship between BMI and alcohol consumption levels in decision making.

ABSTRACT:

Background

Decision-making deficits in obesity and alcohol use disorder (AUD) may contribute to the choice of immediate rewards despite their long-term deleterious consequences.

Methods

Gambling task functional MRI in Human connectome project (HCP) dataset was used to investigate neural activation differences associated with reward or punishment (a key component of decision-making behavior) in 418 individuals with obesity (high BMI) and without obesity (lean BMI) and either at high (HR) or low (LR) risk of AUD based on their alcohol drinking levels.

Results

Interaction between BMI and alcohol drinking was seen in regions of the default mode network (DMN) and those implicated in self-related processing, memory, and salience attribution. ObesityHR relative to obesityLR

SUBMITTER: Agarwal K 

PROVIDER: S-EPMC8528710 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature