Homeostasis and food craving in obesity: a functional MRI study.

ABSTRACT:

Objectives

Food intake in obesity has been found to be reward-based and less contingent on homeostatic needs. Accordingly, previous studies investigating neural processing of food cues observed aberrant processing in reward- and control-related brain regions in obesity. To further investigate the relation between homeostasis and food intake, this study investigated the influence of glucose metabolism on the neuronal response during the regulation of food craving in participants with obesity.

Methods

Twenty-five normal-weight and 25 women with obesity were examined on two occasions after receiving either water or glucose directly into the stomach using a nasogastric tube. Participants were blinded to the type of infusion and were required to refrain from eating for 16 h befor

SUBMITTER: Stopyra MA 

PROVIDER: S-EPMC8528711 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature