Ontology highlight
ABSTRACT:
SUBMITTER: Goldsmith DR
PROVIDER: S-EPMC8528914 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
Goldsmith David R DR Massa Nicholas N Miller Brian J BJ Miller Andrew H AH Duncan Erica E
NPJ schizophrenia 20211020 1
Finding biological predictors and novel mechanisms underlying negative symptoms of schizophrenia is of significant importance given the lack of effective treatments. Increasing data support a role for metabolic dysfunction and inflammation in reward processing deficits in psychiatric illness. Herein, we found an interaction between lipids and inflammation as a predictor of worse negative symptom severity in individuals with schizophrenia. Future studies may seek to further elucidate this relatio ...[more]