Spatially structured yeast communities: Understanding structure formation and regulation with omics tools.

ABSTRACT: Single-celled yeasts form spatially structured populations - colonies and biofilms, either alone (single-species biofilms) or in cooperation with other microorganisms (mixed-species biofilms). Within populations, yeast cells develop in a coordinated manner, interact with each other and differentiate into specialized cell subpopulations that can better adapt to changing conditions (e.g. by reprogramming metabolism during nutrient deficiency) or protect the overall population from external influences (e.g. via extracellular matrix). Various omics tools together with specialized techniques for separating differentiated cells and in situ microscopy have revealed important processes and cell interactions in these structures, which are summarized here. Nevertheless, current knowledge is still on

SUBMITTER: Palkova Z 

PROVIDER: S-EPMC8529026 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature