Meta-analysis of the diagnostic value of exosomal miR-21 as a biomarker for the prediction of cancer.

ABSTRACT:

Background

Early diagnosis of cancer is still the most effective method to increase survival and therapeutically effective patient management. Accumulating studies had exploited exosomes as an indicator for the diagnosis and prognosis of cancer. In addition to exosomes, exosome-derived miRs are widely investigated as a novel biomarker for diagnosis in cancer patients. The aim of this study was to clarify the diagnostic value of ex-miR-21 in cancer.

Methods

Databases were searched for eligible studies up to June, 2021. Studies included in this meta-analysis were reviewed and selected independently by two authors. The data of sensitivity, specificity, diagnostic odds ratio (DOR), and summary receiver operating characteristic curves (SROC) of exosomal miR-21 as a diagnostic bio

SUBMITTER: Liu F 

PROVIDER: S-EPMC8529139 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature