A Systematic Review of Clinical Prediction Rules to Predict Hospitalisation in Children with Lower Respiratory Infection in Primary Care and their Validation in a New Cohort.

ABSTRACT: Background: Our goal was to identify existing clinical prediction rules for predicting hospitalisation due to lower respiratory tract infection (LRTI) in children in primary care, guiding antibiotic therapy. A validation of these rules was then performed in a novel cohort of children presenting to primary care in Malawi with World Health Organisation clinically defined pneumonia. Methods: MEDLINE & EMBASE databases were searched for studies on the development, validation and clinical impact of clinical prediction models for hospitalisation in children with lower respiratory tract infection between January 1^st1946-June 30^th 2021. Two reviewers screened all abstracts and titles independently. The study was conducted in accordance with the Preferred Reporti

SUBMITTER: Wildes DM 

PROVIDER: S-EPMC8529204 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature