Pathogenicity of Seneca Valley virus in pigs and detection in Culicoides from an infected pig farm.

ABSTRACT:

Background

Porcine vesicular disease is caused by the Seneca Valley virus (SVV), it is a novel Picornaviridae, which is prevalent in several countries. However, the pathogenicity of SVV on 5-6 week old pigs and the transmission routes of SVV remain unknown.

Methods

This research mainly focuses on the pathogenicity of the CH-GX-01-2019 strain and the possible vector of SVV. In this study, 5-6 week old pigs infected with SVV (CH-GX-01-2019) and its clinical symptoms (including rectal temperatures and other clinical symptoms) were monitored, qRT-PCR were used to detect the viremia and virus distribution. Neutralization antibody assay was set up during this research. Mosquitoes and Culicoides were collected from pigsties after pigs challenge with SVV, and SVV detection within mo

SUBMITTER: Zhang J 

PROVIDER: S-EPMC8529370 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature