Broad spectrum antimicrobial PDMS-based biomaterial for catheter fabrication.

ABSTRACT:

Background

In addition to the widespread use of antibiotics in healthcare settings, the current COVID-19 pandemic has escalated the emergence of antibiotic resistance. Nosocomial infections among hospitalized patients is a leading site for such resistant microbial colonization due to prolonged use of invasive devices and antibiotics in therapies. Invasive medical devices, especially catheters, are prone to infections that could accelerate the development of resistant microbes. Often, catheters - particularly urinary catheters - are prone to high infection rates. Antibiotic-coated catheters can reduce infection rates and although commercially available, are limited in efficacy and choices.

Methods

Herein, a novel and facile method to fabricate PMDS-based biomaterial for the d

SUBMITTER: Armugam A 

PROVIDER: S-EPMC8529379 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature