Strategies for Antibiotic Administration for Bowel Preparation Among Patients Undergoing Elective Colorectal Surgery: A Network Meta-analysis.

ABSTRACT:

Importance

There are discrepancies in guidelines on preparation for colorectal surgery. While intravenous (IV) antibiotics are usually administered, the use of mechanical bowel preparation (MBP), enemas, and/or oral antibiotics (OA) is controversial.

Objective

To summarize all data from randomized clinical trials (RCTs) that met selection criteria using network meta-analysis (NMA) to determine the ranking of different bowel preparation treatment strategies for their associations with postoperative outcomes.

Data sources

Data sources included MEDLINE, Embase, Cochrane, and Scopus databases with no language constraints, including abstracts and articles published prior to 2021.

Study selection

Randomized studies of adults undergoing elective colorectal surgery wit

SUBMITTER: Woodfield JC 

PROVIDER: S-EPMC8529526 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature