Association of total pre-existing comorbidities with stroke risk: a large-scale community-based cohort study from China.

ABSTRACT:

Background

Comorbidities, any other coexisting diseases in patients with a particular index disease, are known to increase the mortality of a stroke. However, the association of pre-existing comorbidities with stroke risk has not been fully studied.

Methods

This study included 16,246 adults from a prospective community-based cohort with a baseline survey conducted in 2013 in China. Participants were followed up with hospitalization records and the Cause of Death Registry. The association of eight pre-existing comorbidities (coronary heart disease, hyperlipidemia, hypertension, diabetes, previous stroke, chronic obstructive pulmonary disease, nephropathy, and cancer) with stroke risk was analyzed using the Cox proportional hazard model in 2020.

Results

At a median foll

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC8529731 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature