Exercise-induced irregular right heart flow dynamics in adolescents and young adults born preterm.

ABSTRACT:

Background

Preterm birth has been linked to an elevated risk of heart failure and cardiopulmonary disease later in life. With improved neonatal care and survival, most infants born preterm are now reaching adulthood. In this study, we used 4D flow cardiovascular magnetic resonance (CMR) coupled with an exercise challenge to assess the impact of preterm birth on right heart flow dynamics in otherwise healthy adolescents and young adults who were born preterm.

Methods

Eleven young adults and 17 adolescents born preterm (< 32 weeks of gestation and < 1500 g birth weight) were compared to 11 young adult and 18 adolescent age-matched controls born at term. Stroke volume, cardiac output, and flow in the main pulmonary artery were quantified with 4D flow CMR. Kinetic energy and vor

SUBMITTER: Macdonald JA 

PROVIDER: S-EPMC8529801 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature