Respiratory function declines in children with asthma associated with chemical species of fine particulate matter (PM_2.5) in Nagasaki, Japan.

ABSTRACT:

Background

The differential effects of PM_2.5 fractions on children's lung function remain inconclusive. This study aimed to examine whether lung function in asthmatic children was associated with increased PM_2.5 fractions in urban areas in Nagasaki prefecture, Japan, where the air pollution level is relatively low but influenced by transboundary air pollution.

Methods

We conducted a multiyear panel study of 73 asthmatic children (boys, 60.3%; mean age, 8.2 years) spanning spring 2014-2016 in two cities. We collected self-measured peak expiratory flow (PEF) twice a day and daily time-series data for PM_2.5 total mass and its chemical species. We fitted a linear mixed effects model to examine short-term associations between PEF and PM_2.5

SUBMITTER: Kim Y 

PROVIDER: S-EPMC8529805 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature