Relations Among Anhedonia, Reinforcement Learning, and Global Functioning in Help-seeking Youth.

ABSTRACT: Dysfunction in the neural circuits underlying salience signaling is implicated in symptoms of psychosis and may predict conversion to a psychotic disorder in youth at clinical high risk (CHR) for psychosis. Additionally, negative symptom severity, including consummatory and anticipatory aspects of anhedonia, may predict functional outcome in individuals with schizophrenia-spectrum disorders. However, it is unclear whether anhedonia is related to the ability to attribute incentive salience to stimuli (through reinforcement learning [RL]) and whether measures of anhedonia and RL predict functional outcome in a younger, help-seeking population. We administered the Salience Attribution Test (SAT) to 33 participants who met criteria for either CHR or a recent-onset psychotic disorder and 29 hel

SUBMITTER: Akouri-Shan L 

PROVIDER: S-EPMC8530392 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature