Efficacy of naproxen in the management of patients hospitalized with COVID-19 infection: A randomized, double-blind, placebo-controlled, clinical trial.

ABSTRACT:

Background and aims

The current study was done to examine the efficacy of naproxen in the management of patients with COVID-19 infection.

Methods

This randomized, double-blind, placebo-controlled, clinical trial was done on hospitalized adult patients with confirmed COVID-19 infection. Patients were randomly assigned to receive either naproxen (two capsules per day each containing 500 mg naproxen sodium) or placebo (containing starch) for five days along with the routine treatment that was nationally recommended for COVID-19 infection. Clinical symptoms of COVID-19 infection, the time to clinical improvement, blood pressure, laboratory parameters, and death due to COVID-19 infection were considered as the outcome variables in the present study.

Results

Treatment with

SUBMITTER: Asadi M 

PROVIDER: S-EPMC8530771 | biostudies-literature | 2021 Nov-Dec

REPOSITORIES: biostudies-literature