Estimation and removal of spurious echo artifacts in single-voxel MRS using sensitivity encoding.

ABSTRACT:

Purpose

In localized MRS, spurious echo artifacts commonly occur when unsuppressed signal outside the volume of interest is excited and refocused. In the spectral domain, these signals often overlap with metabolite resonances and hinder accurate quantification. Because the artifacts originate from regions separate from the target MRS voxel, this work proposes that sensitivity encoding based on receive-coil sensitivity profiles may be used to separate these signal contributions.

Methods

Numerical simulations were performed to explore the effect of sensitivity-encoded separation for unknown artifact regions. An imaging-based approach was developed to identify regions that may contribute to spurious echo artifacts, and tested for sensitivity-based unfolding of signal on six dat

SUBMITTER: Berrington A 

PROVIDER: S-EPMC8530843 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature