The association of bispectral index values and metrics of cerebral perfusion during cardiopulmonary bypass.

ABSTRACT:

Study objective

Low bispectral index (BIS) values have been associated with adverse postoperative outcomes. However, trials of optimizing BIS by titrating anesthetic administration have reported conflicting results. One potential explanation is that cerebral perfusion may also affect BIS, but the extent of this relationship is not clear. Therefore, we examined whether BIS would be associated with cerebral perfusion during cardiopulmonary bypass, when anesthetic concentration was constant.

Design

Observational cohort study.

Setting

Cardiac operating room.

Patients

Seventy-nine patients with cardiopulmonary bypass surgery were included.

Measurements

Continuous BIS, mean arterial blood pressure (MAP), cerebral blood flow velocity (CBFV), and regional cerebr

SUBMITTER: Liu X 

PROVIDER: S-EPMC8530850 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature