2D:4D Ratio and Autism Spectrum Disorder in Brunei Darussalam.

ABSTRACT:

Background

Despite the global increase in the prevalence of autism spectrum disorders (ASD), relevant research studies are lacking in Brunei Darussalam. Various studies have shown a significant association between a lowered 2D:4D ratio (ratio of second digit/index finger to the fourth digit/ring finger) and ASD, making it one of the potential phenotypic biomarkers for early detection of autism, which is important for early intervention and management.

Objective

The objective of this study is to explore the association between 2D:4D ratio and ASD in Brunei Darussalam, as a potential tool to complement early ASD diagnosis.

Methods

We conducted a case-control study comprising 28 ASD and 62 typically developing (TD) children in the case and control group, respectively (ag

SUBMITTER: Lee SHF 

PROVIDER: S-EPMC8531075 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature