Fever and hypothermia represent two populations of sepsis patients and are associated with outside temperature.

ABSTRACT:

Background

Fever and hypothermia have been observed in septic patients. Their influence on prognosis is subject to ongoing debates.

Methods

We did a secondary analysis of a large clinical dataset from a quality improvement trial. A binary logistic regression model was calculated to assess the association of the thermal response with outcome and a multinomial regression model to assess factors associated with fever or hypothermia.

Results

With 6542 analyzable cases we observed a bimodal temperature response characterized by fever or hypothermia, normothermia was rare. Hypothermia and high fever were both associated with higher lactate values. Hypothermia was associated with higher mortality, but this association was reduced after adjustment for other risk factors. Age,

SUBMITTER: Thomas-Ruddel DO 

PROVIDER: S-EPMC8532310 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature