Metabolic flux sampling predicts strain-dependent differences related to aroma production among commercial wine yeasts.

ABSTRACT:

Background

Metabolomics coupled with genome-scale metabolic modeling approaches have been employed recently to quantitatively analyze the physiological states of various organisms, including Saccharomyces cerevisiae. Although yeast physiology in laboratory strains is well-studied, the metabolic states under industrially relevant scenarios such as winemaking are still not sufficiently understood, especially as there is considerable variation in metabolism between commercial strains. To study the potential causes of strain-dependent variation in the production of volatile compounds during enological conditions, random flux sampling and statistical methods were used, along with experimental extracellular metabolite flux data to characterize the differences in predicted intracellular m

SUBMITTER: Scott WT 

PROVIDER: S-EPMC8532357 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature