Extraction of Aloesin from Aloe vera Rind Using Alternative Green Solvents: Process Optimization and Biological Activity Assessment.

ABSTRACT: Aloesin is an aromatic chromone with increasing applications in the cosmetic and health food industries. To optimize its extraction from the Aloe vera leaf rind, the independent variables time (10-210 min), temperature (25-95 °C) and organic solvent composition (0-100%, w/w) were combined in a central composite design coupled with response surface methodology. The solvents consisted of binary mixtures of water with ethanol, propylene glycol, or glycerol. The aloesin levels quantified in each extract were used as response for optimization. The theoretical models were fitted to the experimental data, statistically validated, and used to obtain the optimal extraction conditions. Then, a dose-response analysis of the solid/liquid ratio (S/L) was performed under the optimal conditions determine

SUBMITTER: Anibarro-Ortega M 

PROVIDER: S-EPMC8533118 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature