Expression Profiles and Prognostic Value of FABPs in Colorectal Adenocarcinomas.

ABSTRACT: Colorectal cancer (CRC) is one of the world's leading causes of cancer-related deaths; thus, it is important to detect it as early as possible. Obesity is thought to be linked to a large rise in the CRC incidence as a result of bad dietary choices, such as a high intake of animal fats. Fatty acid-binding proteins (FABPs) are a set of molecules that coordinate intracellular lipid responses and are highly associated with metabolism and inflammatory pathways. There are nine types of FABP genes that have been found in mammals, which are FABP1-7, FABP9, and FABP12. Each FABP gene has its own roles in different organs of the body; hence, each one has different expression levels in different cancers. The roles of FABP family genes in the development of CR

SUBMITTER: Prayugo FB 

PROVIDER: S-EPMC8533171 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature