Ontology highlight
ABSTRACT:
SUBMITTER: De Vita S
PROVIDER: S-EPMC8533323 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
De Vita Simona S Chini Maria Giovanna MG Saviano Gabriella G Finamore Claudia C Festa Carmen C Lauro Gianluigi G De Marino Simona S Russo Roberto R Avagliano Carmen C Casapullo Agostino A Calignano Antonio A Bifulco Giuseppe G Iorizzi Maria M
Biomolecules 20211009 10
Natural products have been the main source of bioactive molecules for centuries. We tested the biological profile of two metabolites extracted from <i>Gentiana lutea</i> L. by means of computational techniques and in vitro assays. The two molecules (loganic acid and gentiopicroside) were tested in silico using an innovative technique, named Inverse Virtual Screening (IVS), to highlight putative partners among a panel of proteins involved in inflammation and cancer events. A positive binding with ...[more]