The Self and Its Right Insula-Differential Topography and Dynamic of Right vs. Left Insula.

ABSTRACT: Various studies demonstrate a special role of the right compared to the left anterior insula in mediating our self. However, the neural features of the right insula that allow for its special role remain unclear. Presupposing a spatiotemporal model of self-"Basis model of self-specificity" (BMSS)-we here address the following question: what spatial-topographic and temporal-dynamic features render neural activity in the right insula to be more suitable in mediating self-specificity than the left insula? First, applying fMRI, we demonstrate that the right insula (i) exhibits higher degrees of centrality in rest, and (ii) higher context-dependent functional connectivity in a self-specific task among regions of distinct layers of self (intero-, extero-proprioceptive, and mental). Second, using

SUBMITTER: Scalabrini A 

PROVIDER: S-EPMC8533814 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature