Ontology highlight
ABSTRACT:
SUBMITTER: Choi JH
PROVIDER: S-EPMC8533985 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Choi Jong Ho JH Park Sohae S Kim Gi Dae GD Kim Jae Yeon JY Jun Ji Hye JH Bae Si Hyun SH Baik Soon Koo SK Hwang Seong-Gyu SG Kim Gi Jin GJ
Cells 20210924 10
Phosphatase of regenerating liver-1 (PRL-1) controls various cellular processes and liver regeneration. However, the roles of PRL-1 in liver regeneration induced by chorionic-plate-derived mesenchymal stem cells (CP-MSCs) transplantation remain unknown. Here, we found that increased PRL-1 expression by CP-MSC transplantation enhanced liver regeneration in a bile duct ligation (BDL) rat model by promoting the migration and proliferation of hepatocytes. Engrafted CP-MSCs promoted liver function vi ...[more]