Gene Duplications Are At Least 50 Times Less Frequent than Gene Transfers in Prokaryotic Genomes.

ABSTRACT: The contribution of gene duplications to the evolution of eukaryotic genomes is well studied. By contrast, studies of gene duplications in prokaryotes are scarce and generally limited to a handful of genes or careful analysis of a few prokaryotic lineages. Systematic broad-scale studies of prokaryotic genomes that sample available data are lacking, leaving gaps in our understanding of the contribution of gene duplications as a source of genetic novelty in the prokaryotic world. Here, we report conservative and robust estimates for the frequency of recent gene duplications within prokaryotic genomes relative to recent lateral gene transfer (LGT), as mechanisms to generate multiple copies of related sequences in the same genome. We obtain our estimates by focusing on evolutionarily recent ev

SUBMITTER: Tria FDK 

PROVIDER: S-EPMC8536544 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature