Influence of Dietary Compounds on Arsenic Metabolism and Toxicity. Part I-Animal Model Studies.

ABSTRACT: Population and laboratory studies indicate that exposure to various forms of arsenic (As) is associated with many adverse health effects; therefore, methods are being sought out to reduce them. Numerous studies focus on the effects of nutrients on inorganic As (iAs) metabolism and toxicity, mainly in animal models. Therefore, the aim of this review was to analyze the influence of methionine, betaine, choline, folic acid, vitamin B2, B6, B12 and zinc on the efficiency of iAs metabolism and the reduction of the severity of the whole spectrum of disorders related to iAs exposure. In this review, which includes 58 (in vivo and in vitro studies) original papers, we present the current knowledge in the area. In vitro and in vivo animal studies showed that methionine, choline, folic acid, vitamin

SUBMITTER: Sijko M 

PROVIDER: S-EPMC8536957 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature