Putative Role of MCT1 rs1049434 Polymorphism in High-Intensity Endurance Performance: Concept and Basis to Understand Possible Individualization Stimulus.

ABSTRACT: Monocarboxylate transporters (MCTs) have been proposed as important mediators of the exchange between lactate (La-) producer and La- recipient (consumer) cells. Previous studies have suggested that the MCT1 A1470T genotype could be related to different physical performance phenotypes. This study followed the guidelines for Strengthening the Reporting of Genetic Association Studies (STREGA) and aimed to evaluate the distribution of the MCT1 polymorphism rs1049434 in endurance-trained athletes compared to the untrained population. Moreover, this study explored the potential influence of the polymorphism alleles phenotypes on high-intensity exercise performance. In a cross-sectional study fashion, a total of 85 triathletes from northern Spain were genotyped for MCT1 rs1049434 and compared to

SUBMITTER: Ramirez de la Piscina-Viudez X 

PROVIDER: S-EPMC8537363 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature