Insights into the Resistome and Phylogenomics of a ST195 Multidrug-Resistant Acinetobacter baumannii Clinical Isolate from the Czech Republic.

ABSTRACT: Increasing antimicrobial resistance in nosocomial pathogens, such as Acinetobacter baumannii, is becoming a serious threat to public health. It is necessary to detect β-lactamase-producing microorganisms in clinical settings to be able to control the spread of carbapenem resistance. This study was conducted to evaluate the presence of β-lactamases in a selected clinical isolate of A. baumannii of ST2^P/ST195^Ox and to characterize possible enzymes, as well as its β-lactam resistome, using PCR and whole-genome sequencing analysis. PCR and sequencing confirmed that the isolate harbored five bla gene alleles, namely, bla_ADC-73, bla_TEM-1, bla_OXA-23, bla_OXA-58 an

SUBMITTER: Mlynarcik P 

PROVIDER: S-EPMC8537504 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature