Carrot Consumption Frequency Associated with Reduced BMI and Obesity through the SNP Intermediary rs4445711.

ABSTRACT: It is unclear whether genetic interactions are involved in the association between vegetable intake and reduced body mass index (BMI) or obesity. We conducted a comprehensive search for single nucleotide polymorphisms (SNPs) which are associated with the interaction between vegetable intake frequency and BMI or obesity. We performed a genome-wide association analysis to evaluate the genetic interactions between self-reported intake of vegetables such as carrot, broccoli, spinach, other green vegetables (green pepper and green beans), pumpkin, and cabbage with BMI and obesity, which is defined as a BMI ≥ 25.0 kg/m² in the Japanese population (n = 12,225). The mean BMI and prevalence of obesity was 23.9 ± 3.4 kg/m² and 32.3% in men and 22.1 ± 3.8 kg/m²

SUBMITTER: Fujihara K 

PROVIDER: S-EPMC8538500 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature