Coinfection and Interference Phenomena Are the Results of Multiple Thermodynamic Competitive Interactions.

ABSTRACT: Biological, physical and chemical interaction between one (or more) microorganisms and a host organism, causing host cell damage, represents an infection. Infection of a plant, animal or microorganism with a virus can prevent infection with another virus. This phenomenon is known as viral interference. Viral interference is shown to result from two types of interactions, one taking place at the cell surface and the other intracellularly. Various viruses use different receptors to enter the same host cell, but various strains of one virus use the same receptor. The rate of virus-receptor binding can vary between different viruses attacking the same host, allowing interference or coinfection. The outcome of the virus-virus-host competition is determined by the Gibbs energies of binding and g

SUBMITTER: Popovic M 

PROVIDER: S-EPMC8538544 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature