Characterization of Hydrophilic Polymers as a Syringe Extrusion 3D Printing Material for Orodispersible Film.

ABSTRACT: The application of hydrophilic polymers in designing and three-dimensional (3D) printing of pharmaceutical products in various dosage forms has recently been paid much attention. Use of hydrophilic polymers and syringe extrusion 3D printing technology in the fabrication of orodispersible films (ODFs) might hold great potential in rapid drug delivery, personalized medicine, and manufacturing time savings. In this study, the feasibility of 3D-printed ODFs fabrication through a syringe extrusion 3D printing technique and using five different hydrophilic polymers (e.g., hydroxypropyl methylcellulose E15, hydroxypropyl methylcellulose E50, high methoxyl pectin, sodium carboxymethylcellulose, and hydroxyethylcellulose) as film-forming polymers and printing materials has been investigated. Rheolo

SUBMITTER: Panraksa P 

PROVIDER: S-EPMC8540066 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature