Systematic review of invasive meningococcal disease epidemiology in the Eastern Mediterranean and North Africa region.

ABSTRACT:

Background

Invasive meningococcal disease (IMD) represents a global health burden. However, its epidemiology in the Eastern Mediterranean (EM) and North Africa (NA) regions is currently not well understood. This review had four key objectives: to describe asymptomatic meningococcal carriage, IMD epidemiology (e.g. serogroup prevalence, case-fatality rates [CFRs]), IMD presentation and management (e.g. clinical diagnosis, antibiotic treatments) and economic impact and evaluation (including health technology assessment [HTA] recommendations) in EM and NA.

Methods

A systematic literature search (MEDLINE and EMBASE) was conducted (January 2000 to February 2021). Search strings included meningococcal disease and the regions/countries of interest. Identified publications were scre

SUBMITTER: Dogu AG 

PROVIDER: S-EPMC8540099 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature