Microbiome Changes after Type 2 Diabetes Treatment: A Systematic Review.

ABSTRACT: Background and objectives: Although the role of the gut microbiome in type 2 diabetes (T2D) pathophysiology is evident, current systematic reviews and meta-analyses analyzing T2D treatment mainly focus on metabolic outcomes. The objective of this study is to evaluate the microbiome and metabolic changes after different types of treatment in T2D patients. Materials and Methods: A systematic search of PubMed, Wiley online library, Science Direct, and Cochrane library electronic databases was performed. Randomized controlled clinical trials published in the last five years that included T2D subjects and evaluated the composition of the gut microbiome alongside metabolic outcomes before and after conventional or alternative glucose lowering therapy were selected. Microbiome changes were evalua

SUBMITTER: Merkevicius K 

PROVIDER: S-EPMC8540512 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature