The ALGOVUE Clinical Trial: Effects of the Daily Consumption of Eggs Enriched with Lutein and Docosahexaenoic Acid on Plasma Composition and Macular Pigment Optical Density.

ABSTRACT:

Background

Carotenoids and docosahexaenoic acid (DHA) were identified as essential components for eye health and are both naturally present in eggs.

Objective

We aimed to evaluate the effect of the daily consumption of two eggs enriched with lutein/zeaxanthin and DHA on macular pigment optical density (MPOD) and on circulating xanthophyll and fatty acid concentrations in healthy participants.

Methods

Ninety-nine healthy volunteers consumed either two standard eggs or two enriched eggs per day for 4 months. MPOD was measured at baseline (V0) and at follow-up (V4) using a modified confocal scanning laser ophthalmoscope (primary outcome). Blood samples were collected to determine total plasma and lipoprotein fatty acids and lutein/zeaxanthin compositions at V0 and V4 (se

SUBMITTER: Schnebelen-Berthier C 

PROVIDER: S-EPMC8541434 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature