Facile Synthesis of Gallium (III)-Chitosan Complexes as Antibacterial Biomaterial.

ABSTRACT: Even though antibiotic treatment remains one of the most common tools to handle bacterial infections, the excessive antibiotic concentration at the target site may lead to undesired effects. Aiming at the fabrication of antibiotic-free biomaterials for antibacterial applications, in this work, we propose the synthesis of gallium (III)-chitosan (Ga (III)-CS) complexes with six different gallium concentrations via an in situ precipitation method. Fourier Transform infrared spectroscopy indicated the chelation of chitosan with Ga (III) by peak shifts and changes in the relative absorbance of key spectral bands, while energy-dispersive X-ray spectroscopy indicated the homogenous distribution of the metal ions within the polymer matrix. Additionally, similar to CS, all Ga (III)-CS complexes sho

SUBMITTER: Akhtar MA 

PROVIDER: S-EPMC8541496 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature