Thermodynamic Study of Oxidovanadium(IV) with Kojic Acid Derivatives: A Multi-Technique Approach.

ABSTRACT: The good chelating properties of hydroxypyrone (HPO) derivatives towards oxidovanadium(IV) cation, V^IVO²⁺, constitute the precondition for the development of new insulin-mimetic and anticancer compounds. In the present work, we examined the V^IVO²⁺ complex formation equilibria of two kojic acid (KA) derivatives, L4 and L9, structurally constituted by two kojic acid units linked in position 6 through methylene diamine and diethyl-ethylenediamine, respectively. These chemical systems have been characterized in solution by the combined use of various complementary techniques, as UV-vis spectrophotometry, potentiometry, NMR and EPR spectroscopy, ESI-MS spectrometry, and DFT calculations. The thermodynamic approach allowed proposing a chemical coordina

SUBMITTER: Cappai R 

PROVIDER: S-EPMC8541509 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature