Response to BotulinumtoxinA in a migraine cohort with multiple comorbidities and widespread pain.

ABSTRACT:

Background

The phase III research evaluating migraine prophylaxis therapy (PREEMPT) protocol was developed in low-risk migraine patients. We studied longitudinal response to treatment in a sequential retrospective observational cohort to evaluate predictors of effectiveness in patients with multiple overlapping pain syndromes treated in a quaternary pain management clinic.

Methods

We evaluated indicators of individual response in 402 consecutive chronic migraine patients who provided demographic information and used the Collaborative Health Outcomes Information Registry.

Results

The patients were middle aged 47 (38-56) median (IQR) years old and 83% women. They reported multiple complex pain problems with 11 (6-18) regions represented on a pain body map. Evaluated wit

SUBMITTER: Barad M 

PROVIDER: S-EPMC8541790 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature