Intrapartum group B Streptococcal prophylaxis and childhood weight gain.

ABSTRACT:

Objective

To determine the difference in rate of weight gain from birth to 5 years based on exposure to maternal group B streptococcal (GBS) intrapartum antibiotic prophylaxis (IAP).

Design

Retrospective cohort study of 13 804 infants.

Setting

Two perinatal centres and a primary paediatric care network in Philadelphia.

Participants

Term infants born 2007-2012, followed longitudinally from birth to 5 years of age.

Exposures

GBS IAP defined as penicillin, ampicillin, cefazolin, clindamycin or vancomycin administered ≥4 hours prior to delivery to the mother. Reference infants were defined as born to mothers without (vaginal delivery) or with other (caesarean delivery) intrapartum antibiotic exposure.

Outcomes

Difference in rate of weight change from

SUBMITTER: Mukhopadhyay S 

PROVIDER: S-EPMC8542613 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature