Ontology highlight
ABSTRACT:
SUBMITTER: Dokmai N
PROVIDER: S-EPMC8542641 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
Dokmai Natnatee N Kockan Can C Zhu Kaiyuan K Wang XiaoFeng X Sahinalp S Cenk SC Cho Hyunghoon H
Cell systems 20210826 10
Genotype imputation is an essential tool in genomics research, whereby missing genotypes are inferred using reference genomes to enhance downstream analyses. Recently, public imputation servers have allowed researchers to leverage large-scale genomic data resources for imputation. However, privacy concerns about uploading one's genetic data to a server limit the utility of these services. We introduce a secure hardware-based solution for privacy-preserving genotype imputation, which keeps the in ...[more]