Prognostic Significance of Urinary Biomarkers in Patients Hospitalized With COVID-19.

ABSTRACT:

Rationale & objective

Acute kidney injury (AKI) is common in patients with coronavirus disease 2019 (COVID-19) and associated with poor outcomes. Urinary biomarkers have been associated with adverse kidney outcomes in other settings and may provide additional prognostic information in patients with COVID-19. We investigated the association between urinary biomarkers and adverse kidney outcomes among patients hospitalized with COVID-19.

Study design

Prospective cohort study.

Setting & participants

Patients hospitalized with COVID-19 (n=153) at 2 academic medical centers between April and June 2020.

Exposure

19 urinary biomarkers of injury, inflammation, and repair.

Outcome

Composite of KDIGO (Kidney Disease: Improving Global Outcomes) stage 3 AKI, require

SUBMITTER: Menez S 

PROVIDER: S-EPMC8542781 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature