Evaluating the Cost of Pharmaceutical Purification for a Long-Duration Space Exploration Medical Foundry.

ABSTRACT: There are medical treatment vulnerabilities in longer-duration space missions present in the current International Space Station crew health care system with risks, arising from spaceflight-accelerated pharmaceutical degradation and resupply lag times. Bioregenerative life support systems may be a way to close this risk gap by leveraging in situ resource utilization (ISRU) to perform pharmaceutical synthesis and purification. Recent literature has begun to consider biological ISRU using microbes and plants as the basis for pharmaceutical life support technologies. However, there has not yet been a rigorous analysis of the processing and quality systems required to implement biologically produced pharmaceuticals for human medical treatment. In this work, we use the equivalent system

SUBMITTER: McNulty MJ 

PROVIDER: S-EPMC8542935 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature