Administration of parenteral nutrition during therapeutic hypothermia: a population level observational study using routinely collected data held in the National Neonatal Research Database.

ABSTRACT:

Background

Parenteral nutrition is commonly administered during therapeutic hypothermia. Randomised trials in critically ill children indicate that parenteral nutrition may be harmful.

Objective

To examine the association between parenteral nutrition during therapeutic hypothermia and clinically important outcomes.

Design

Retrospective, population-based cohort study using the National Neonatal Research Database; propensity scores were used to create matched groups for comparison.

Setting

National Health Service neonatal units in England, Scotland and Wales.

Participants

6030 term and near-term babies, born 1/1/2010 and 31/12/2017, who received therapeutic hypothermia; 2480 babies in the matched analysis.

Exposure

We compared babies that received a

SUBMITTER: Gale C 

PROVIDER: S-EPMC8543212 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature